Lexus RX300 1999-2003 Diagnostic in Advance Auto Parts show P0021 Camshaft Position Timing Sensor need to me replaced.
Also:
Misfire P0300,
P0304 CYLINDER 4, 5 AND 6

Symptoms: While driving in about 60 mph feels like transmission does not switch correctly it idle a little then shift like a punch. Never happens before.

If idling on tachometer show less then 1000 rpm and not stable car shaking, rpm move up and down.

Tried solutions:
Replaced Spark plugs;
Replaced Coils on 4, 5, 6
Replaced Camshaft Position Timing Sensor (bought from Pep Boys)

Nothing change!

Same symptoms!

I even removed sensor and start a car for minute and nothing changed.

Guess maybe Pep Boys sold me defective sensor or my problem not relay to all what I did.

Just in case some one looking this is position of the sensor on my Lexus RX-300:

lexus rx 300, camshafts, misfires, p0021, p0304,
Will appreciate help.

thank you